Metformin prevents oxidative stress and apoptosis of ovarian granulosa cells in polycystic ovary syndrome via activation of Nrf2-HO-1 pathway
Objective The purpose of the study is to investigate therapeutic effects of metformin on improving PCOS and the underlying mechanism.Methods PCOS modeling and metformin treatment in rats was performed by subcutaneous injection of dehydroepiandrosterone (DHEA) daily, high-fat diet feeding, and intrag...
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| Hlavní autoři: | , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Taylor & Francis Group
2025-12-01
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| Edice: | Gynecological Endocrinology |
| Témata: | |
| On-line přístup: | https://www.tandfonline.com/doi/10.1080/09513590.2025.2528815 |
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