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Proteomic profiling identifies SPP1 associated with rapidly progressive interstitial lung disease in anti-MDA5-positive dermatomyositis

Abstract Background Anti-melanoma differentiation-associated gene five antibody positive (MDA5+) dermatomyositis (DM) is significantly associated with rapidly progressive interstitial lung disease (RP-ILD). Early detection of RP-ILD remains a major challenge. This study aims to identify and validate...

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Principais autores: Yulu Qiu, Xiaoke Feng, Chang Liu, Yumeng Shi, Lingxiao Xu, Hanxiao You, Lei Wang, Chengyin Lv, Fang Wang, Wenfeng Tan
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2024-01-01
coleção:Arthritis Research & Therapy
Assuntos:
Dermatomyositis
MDA5
Interstitial lung disease
RP-ILD
Biomarker
Acesso em linha:https://doi.org/10.1186/s13075-023-03243-z
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