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SIV escape mutants in rhesus macaques vaccinated with NEF-derived lipopeptides and challenged with pathogenic SIVmac251

<p>Abstract</p> <p>Background</p> <p>Emergence of viral variants that escape CTL control is a major hurdle in HIV vaccination unless such variants affect gene regions that are essential for virus replication. Vaccine-induced multispecific CTL could also be able to control viral variants replication....

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Principais autores: Mortara Lorenzo, Coutsinos Zoe, Letourneur Franck, Villefroy Pascale, Beyer Christian, Gras-Masse Helene, Guillet Jean-Gerard, Bourgault-Villada Isabelle
Formato: Artigo
Idioma:Inglês
Publicado: BMC 2006-08-01
Series:Virology Journal
Acceso en liña:http://www.virologyj.com/content/3/1/65
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