Enhanced discrimination of Clostridioides difficile transmission using whole-genome sequencing and in silico multi-locus variable number tandem repeat analysis

ABSTRACT Whole-genome sequencing (WGS) is used to establish genetic relatedness of bacteria and track outbreaks in healthcare settings. While WGS provides sufficient discriminatory power to make inferences about genetic relatedness and transmission for most bacterial species, WGS for Clostridioides...

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Autori principali:	Alexander J. Sundermann, Emma G. Mills, Vatsala Rangachar Srinivasa, Marissa P. Griffith, Deena Ereifej, Kady D. Waggle, Nathan J. Raabe, Graham M. Snyder, Daria Van Tyne, Lora Lee Pless, Lee H. Harrison
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology 2025-12-01
Serie:	Microbiology Spectrum
Soggetti:	Clostridioides difficile multi-locus variable number tandem repeat analysis whole-genome sequencing genomic epidemiology hospital-associated infections outbreaks
Accesso online:	https://journals.asm.org/doi/10.1128/spectrum.03287-24
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