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Using the Appropriate Formula for QT Measurement Can Save Lives

CDK 4/6 inhibitors, in combination with endocrine therapy, are the standard of care for patients with endocrine- sensitive advanced breast cancer. This class of drug, however, is associated with QT prolongation, which serves as a surrogate marker for Torsades de Pointes (TdP), a cause of life-threat...

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Main Authors: Taher Al-Tweigeri, Susan Dent, Adher Al Sayed, Dania Mohty, Kausar Suleman, Dahish Ajarim, Hussein Raef, Najmeddine Echahidi
Format: Artigo
Language:Inglês
Published: Wolters Kluwer Medknow Publications 2022-01-01
Series:Hematology/Oncology and Stem Cell Therapy
Subjects:
qtc interval
qt correction
cancer treatment
drug safety
cdk4/6 inhibitors
arrhythmia
Online Access:https://journals.lww.com/10.1016/j.hemonc.2021.06.001
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