Impact of Tigecycline Versus Other Antibiotics on the Fecal Metabolome and on Colonization Resistance to Clostridium difficile in Mice

Background: The glycylcycline antibiotic tigecycline may have a relatively low propensity to promote Clostridium difficile infection in part because it causes less disruption of the indigenous intestinal microbiota than other broad-spectrum antibiotics.  We used a mouse model to compare the compare...

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Detalhes bibliográficos

Principais autores:	Robin L.P. Jump, David Kraft, Kelly Hurless, Alex Polinkovsky, Curtis J. Donskey
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Case Western Reserve University 2017-01-01
coleção:	Pathogens and Immunity
Assuntos:	Tigecycline Clostridium difficile ceftriaxone piperacillin/tazobactam linezolid metabolomics colonization resistance
Acesso em linha:	https://paijournal.com/index.php/paijournal/article/view/159
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