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Rare single PML::RARA fusion transcript from insertion on derivative chromosome 17 in acute promyelocytic leukemia

Abstract Over 90% of patients with acute promyelocytic leukemia (APL) harbor the typical translocation characterized by the dual fusion of PML::RARA and RARA::PML transcripts. Here, we report a case with a single fusion of PML::RARA formed on der(17), without the RARA::PML fusion, and the patient re...

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Principais autores: Ping Yang, Daniel Cassidy, Catalina Amador, Sangeetha Venugopal
Formato: Artigo
Idioma:Inglês
Publicado: BMC 2025-09-01
Series:Molecular Cytogenetics
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Acceso en liña:https://doi.org/10.1186/s13039-025-00727-2
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