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Targeting Notch and EGFR signaling in human mucoepidermoid carcinoma

Abstract Mucoepidermoid carcinoma (MEC) is the most common type of salivary gland cancers and patients with advanced, metastatic, and recurrent MECs have limited therapeutic options and poor treatment outcomes. MEC is commonly associated with a chromosomal translocation t(11;19) (q14-21;p12-13) that...

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Bibliografiske detaljer
Principais autores: Wei Ni, Zirong Chen, Xin Zhou, Rongqiang Yang, Mu Yu, Jianrong Lu, Frederic J. Kaye, Lizi Wu
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2021-01-01
Serier:Signal Transduction and Targeted Therapy
Online adgang:https://doi.org/10.1038/s41392-020-00388-0
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