Engineering osmolysis susceptibility in Cupriavidus necator and Escherichia coli for recovery of intracellular products

Abstract Background Intracellular biomacromolecules, such as industrial enzymes and biopolymers, represent an important class of bio-derived products obtained from bacterial hosts. A common key step in the downstream separation of these biomolecules is lysis of the bacterial cell wall to effect rele...

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Bibliografische Detailangaben

Hauptverfasser:	Jeremy David Adams, Kyle B. Sander, Craig S. Criddle, Adam P. Arkin, Douglas S. Clark
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	BMC 2023-04-01
Schriftenreihe:	Microbial Cell Factories
Schlagworte:	Osmolysis Bioseparations Bacteria cell lysis Adaptive laboratory evolution Mechanosensitive channel
Online-Zugang:	https://doi.org/10.1186/s12934-023-02064-8
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