Steroid-mediated liver steatosis is CD1d-dependent, while steroid-induced liver necrosis, inflammation, and metabolic changes are CD1d-independent

Abstract Introduction Glucocorticoids contribute to the pathogenesis of non-alcoholic fatty liver disease (NAFLD). Natural killer T cells play a role in the pathogenesis of NAFLD and response to steroids. The present study aimed to determine the role of CD1d in steroid-mediated metabolic derangement...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής

Κύριοι συγγραφείς:	Tomer Adar, Ami Ben Ya’acov, Yehudit Shabat, Meir Mizrahi, Lida Zolotarov, Yoav Lichtenstein, Yaron Ilan
Μορφή:	Artigo
Γλώσσα:	Inglês
Έκδοση:	BMC 2022-04-01
Σειρά:	BMC Gastroenterology
Θέματα:	Steroids NKT cells NAFLD NASH Glycosphingolipids Glucocerebroside
Διαθέσιμο Online:	https://doi.org/10.1186/s12876-022-02242-9
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