Gibberellin derivative GA-13315 overcomes multidrug resistance in breast cancer by up-regulating BMP6 expression

Chemoresistance represents a major obstacle in breast cancer treatment. Bone morphogenetic protein 6 (BMP6) was reported to participate in the occurrence and development of various tumors. In the present study, the results of transcriptome sequencing, qRT-PCR and western blot analysis revealed that...

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Detalhes bibliográficos

Principais autores:	Xianqiang Luo, Guohui Wang, Yuting Wang, Meichen Wang, Zhuomin Tan, Min Luo, Limei Zhang, Yan Song, Yinnong Jia, Hongyu Zhou, Chen Qing
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2022-11-01
coleção:	Frontiers in Pharmacology
Assuntos:	GA-13315 (GA5) multidrug resistance (MDR) doxorubicin (DOX) bone morphogenetic protein 6 (BMP6) ERK P-gp
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fphar.2022.1059365/full
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