Integrating serum pharmacochemistry and network pharmacology to explore potential compounds and mechanisms of Alpiniae oxyphyllae fructus in the treatment of cellular senescence in diabetic kidney disease

BackgroundDiabetic kidney disease (DKD), one of the microvascular complications in patients with diabetes mellitus, is a common cause of end-stage renal disease. Cellular senescence is believed to be an essential participant in the pathogenesis of DKD. Although there is evidence that Alpiniae oxyphy...

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Bibliografische Detailangaben

Hauptverfasser:	Zijie Yan, Lin Zhang, Yu Kang, Shuman Liu, Xiaoyan Li, Lidan Li, Kai Rui, Man Xiao, Yiqiang Xie
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Frontiers Media S.A. 2024-07-01
Schriftenreihe:	Frontiers in Medicine
Schlagworte:	diabetic kidney disease traditional Chinese medicine cellular senescence Alpiniae oxyphyllae fructus UHPLC-QTOF-MS network pharmacology
Online-Zugang:	https://www.frontiersin.org/articles/10.3389/fmed.2024.1424644/full
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