Study protocol for ADAPT-TDM: A beta-lactam antibiotic Dose AdaPtation feasibility randomised controlled Trial using Therapeutic Drug Monitoring

Introduction Critically ill patients are at risk of suboptimal beta-lactam antibiotic (beta-lactam) exposure due to the impact of altered physiology on pharmacokinetics. Suboptimal concentrations can lead to treatment failure or toxicity. Therapeutic drug monitoring (TDM) involves adjusting doses ba...

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Autores principales:	Darshini Ayton, Andrew A Udy, Sebastian Wicha, Adam Jenney, Sue J Lee, Anton Y Peleg, Rekha Pai Mangalore, Ming Gene Chai, Jeffrey Pope, Alexander Padiglione, Arne Diehl, Llyod Roberts, Kirsty Sim, Philip Rawson-Harris, Hans G Schneider, Trish N Peel
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	BMJ Publishing Group 2024-06-01
Colección:	BMJ Open
Acceso en línea:	https://bmjopen.bmj.com/content/14/6/e083635.full
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