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Sleep and circadian disruption reshape immune homeostasis in oral tissues: mechanistic roles of melatonin and cortisol in periodontal disease and xerostomia

Sleep disturbance has emerged as a major modifier of immune homeostasis in chronic inflammatory diseases, yet its immunological relevance to oral tissues remains incompletely integrated. Accumulating evidence indicates that sleep and oral inflammatory diseases are linked through coordinated neuroend...

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Principais autores: Mu-Hsin Chen, Yu-Ching Hung, Wei-Ni Kuo, Hsuan-Yu Hsu, I-Ta Lee, Cheng-Yu Tsai, Arnab Majumdar, Tien-Li Ma
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2026-04-01
Serier:Frontiers in Immunology
Fag:
circadian disruption
cortisol
immune homeostasis
melatonin
oral inflammatory diseases
Online adgang:https://www.frontiersin.org/articles/10.3389/fimmu.2026.1781288/full
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