N-Acetylmuramic Acid (MurNAc) Auxotrophy of the Oral Pathogen Tannerella forsythia: Characterization of a MurNAc Kinase and Analysis of Its Role in Cell Wall Metabolism

Tannerella forsythia is an anaerobic, Gram-negative oral pathogen that thrives in multispecies gingival biofilms associated with periodontitis. The bacterium is auxotrophic for the commonly essential bacterial cell wall sugar N-acetylmuramic acid (MurNAc) and, thus, strictly depends on an exogenous...

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Bibliografische Detailangaben

Hauptverfasser:	Isabel Hottmann, Valentina M. T. Mayer, Markus B. Tomek, Valentin Friedrich, Matthew B. Calvert, Alexander Titz, Christina Schäffer, Christoph Mayer
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Frontiers Media S.A. 2018-01-01
Schriftenreihe:	Frontiers in Microbiology
Schlagworte:	oral pathogen red complex consortium N-acetylmuramic acid kinase MurNAc auxotrophy peptidoglycan metabolism cell wall recycling
Online-Zugang:	http://journal.frontiersin.org/article/10.3389/fmicb.2018.00019/full
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