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The Challenge of Dimethyl Fumarate Repurposing in Eye Pathologies

Dimethyl fumarate (DMF) is a small molecule currently approved and used in the treatment of psoriasis and multiple sclerosis due to its immuno-modulatory, anti-inflammatory, and antioxidant properties. As an Nrf2 activator through Keap1 protein inhibition, DMF unveils a potential therapeutical use t...

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Autori principali: Federico Manai, Stefano Govoni, Marialaura Amadio
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI AG 2022-12-01
Serie:Cells
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Accesso online:https://www.mdpi.com/2073-4409/11/24/4061
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