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Harnessing unprotected deactivated amines and arylglyoxals in the Ugi reaction for the synthesis of fused complex nitrogen heterocycles

Piperazines and diazepines are examples of nitrogen heterocycles present in many marketed drugs highlighting their importance in the discovery of novel bioactive compounds. However, their synthesis often faces challenges, including complex functionalization and lengthy reaction sequences. Multicompo...

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Autors principals: Javier Gómez-Ayuso, Pablo Pertejo, Tomás Hermosilla, Israel Carreira-Barral, Roberto Quesada, María García-Valverde
Format: Artigo
Idioma:Inglês
Publicat: Beilstein-Institut 2024-07-01
Col·lecció:Beilstein Journal of Organic Chemistry
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Accés en línia:https://doi.org/10.3762/bjoc.20.154
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