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Click-correlative light and electron microscopy (click-AT-CLEM) for imaging and tracking azido-functionalized sphingolipids in bacteria

Abstract Sphingolipids, including ceramides, are a diverse group of structurally related lipids composed of a sphingoid base backbone coupled to a fatty acid side chain and modified terminal hydroxyl group. Recently, it has been shown that sphingolipids show antimicrobial activity against a broad ra...

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Detalhes bibliográficos
Principais autores: Simon Peters, Lena Kaiser, Julian Fink, Fabian Schumacher, Veronika Perschin, Jan Schlegel, Markus Sauer, Christian Stigloher, Burkhard Kleuser, Jürgen Seibel, Alexandra Schubert-Unkmeir
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Portfolio 2021-02-01
coleção:Scientific Reports
Acesso em linha:https://doi.org/10.1038/s41598-021-83813-w
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