Heparan sulfate is an important mediator of Ebola virus infection in polarized epithelial cells

Abstract Background Currently, no FDA-approved vaccines or treatments are available for Ebola virus disease (EVD), and therapy remains largely supportive. Ebola virus (EBOV) has broad tissue tropism and can infect a variety of cells including epithelial cells. Epithelial cells differ from most other...

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Главные авторы:	Manasi Tamhankar, Dawn M. Gerhardt, Richard S. Bennett, Nicole Murphy, Peter B. Jahrling, Jean L. Patterson
Формат:	Artigo
Язык:	Inglês
Опубликовано:	BMC 2018-08-01
Серии:	Virology Journal
Предметы:	Ebola virus Caco-2 Polarized cells Heparan sulfate
Online-ссылка:	http://link.springer.com/article/10.1186/s12985-018-1045-0
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