Artesunate Induces G0/G1 Phase Arrest in Tumor Cells and Associates With Cyclin‐Dependent Kinase 4 (CDK4)

ABSTRACT Background Non‐small cell lung cancer (NSCLC) is the leading cause of cancer‐related death worldwide. Cyclin‐dependent kinase 4 (CDK4) is a well‐validated oncogenic driver in NSCLC, yet current CDK4 inhibitors—predominantly based on the aminopyrimidine scaffold—are limited by structural hom...

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主要な著者:	Xinyu Chi, Qicong Chen, Gang Wang, Honglin Luo, Shenhong Qu, Xiaosu Zou
フォーマット:	Artigo
言語:	Inglês
出版事項:	Wiley 2026-05-01
シリーズ:	Cancer Medicine
主題:	artesunate CDK4 cell cycle arrest human proteome microarray lung cancer
オンライン･アクセス:	https://doi.org/10.1002/cam4.71907
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