Noggin Inhibits IL-1β and BMP-2 Expression, and Attenuates Cartilage Degeneration and Subchondral Bone Destruction in Experimental Osteoarthritis

Osteoarthritis (OA) is a chronic inflammatory and progressive joint disease that results in cartilage degradation and subchondral bone remodeling. The proinflammatory cytokine interleukin 1 beta (IL-1β) is abundantly expressed in OA and plays a crucial role in cartilage remodeling, although its role...

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Principais autores:	Szu-Yu Chien, Chun-Hao Tsai, Shan-Chi Liu, Chien-Chung Huang, Tzu-Hung Lin, Yu-Zhen Yang, Chih-Hsin Tang
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2020-04-01
coleção:	Cells
Assuntos:	osteoarthritis interleukin-1β bone morphogenetic protein 2 cartilage remodeling
Acesso em linha:	https://www.mdpi.com/2073-4409/9/4/927
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