Targeted muscle reinnervation attenuates neuropathic pain and neuroma development in a rat model of tibial nerve transection

BackgroundPeripheral nerve injuries often lead to painful neuroma formation and chronic neuropathic pain, and the optimal surgical strategy for prevention remains debated. Targeted muscle reinnervation (TMR), regenerative peripheral nerve interfaces (RPNI), and nerve-in-muscle implantation (NIM) are...

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Detalhes bibliográficos

Principais autores:	Li Li, Ainizier Yalikun, QiYue Zhang, DeBin Xiong, Tao Jiang, Fan Bu, QingTang Zhu, Aihemaitijiang Yusufu
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2026-02-01
coleção:	Frontiers in Bioengineering and Biotechnology
Assuntos:	nerve transection neuroma prevention neuropathic pain rat model targeted muscle reinnervation
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fbioe.2026.1758496/full
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