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Lipopolysaccharide directly inhibits bicarbonate absorption by the renal outer medullary collecting duct

Abstract Acidosis is associated with E. coli induced pyelonephritis but whether bacterial cell wall constituents inhibit HCO3 transport in the outer medullary collecting duct from the inner stripe (OMCDi) is not known. We examined the effect of lipopolysaccharide (LPS), on HCO3 absorption in isolate...

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Váldodahkkit: Shuichi Tsuruoka, Jeffrey M. Purkerson, George J. Schwartz
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: Nature Portfolio 2020-11-01
Ráidu:Scientific Reports
Liŋkkat:https://doi.org/10.1038/s41598-020-77363-w
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