Comparison of apoA-I helical structure and stability in discoidal and spherical HDL particles by HX and mass spectrometry

Elucidation of apoA-I secondary structure in spherical plasma HDL particles is essential for understanding HDL structure and function at the molecular level. To provide this information, we have applied hydrogen exchange (HX) and mass spectrometry methods to compare apoA-I secondary structure in dis...

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Bibliografische Detailangaben

Hauptverfasser:	Palaniappan Sevugan Chetty, David Nguyen, Margaret Nickel, Sissel Lund-Katz, Leland Mayne, S.Walter Englander, Michael C. Phillips
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Elsevier 2013-06-01
Schriftenreihe:	Journal of Lipid Research
Schlagworte:	amphipathic α-helix cholesterol lipoprotein phospholipid hydrogen exchange
Online-Zugang:	http://www.sciencedirect.com/science/article/pii/S0022227520357151
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