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Preclinical activity of allogeneic SLAMF7-specific CAR T-cells (UCARTCS1) in multiple myeloma

Background Autologous BCMA-specific CAR T-cell therapies have substantial activity in multiple myeloma (MM). However, due to logistical limitations and BCMAlow relapses, there is a need for alternatives. UCARTCS1 cells are ‘off-the-shelf’ allogeneic CAR T-cells derived from healthy donors targeting...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Roman Galetto, Tuna Mutis, Sonja Zweegman, Isabelle Chion-Sotinel, Charlotte L B M Korst, Chloe O’Neill, Wassilis S C Bruins, Meliha Cosovic, Inoka Twickler, Christie P M Verkleij, Diane Le Clerre, Maria Themeli, Niels W C J van de Donk
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMJ Publishing Group 2024-07-01
Schriftenreihe:Journal for ImmunoTherapy of Cancer
Online-Zugang:https://jitc.bmj.com/content/12/7/e008769.full
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