Pharmacological manipulation of nested oscillations in human iPSC-derived 2D neuronal networks

Summary: Dynamically coupled neural networks are fundamental to human cognition and behavior and are disrupted in neurodevelopmental disorders. The formation and dissolution of functional networks is thought to be driven by synchronized oscillatory bursts across large populations of neurons. The mec...

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Detalhes bibliográficos

Principais autores:	Deborah Pré, Christian Cazares, Alexander T. Wooten, Haowen Zhou, Isabel Onofre, Ashley Neil, Todd Logan, Ruilong Hu, Jan H. Lui, Bradley Voytek, Anne G. Bang
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2026-03-01
coleção:	Neurobiology of Disease
Assuntos:	Human induced pluripotent stem cell (hiPSC) Oscillations Excitation/inhibition Multi-electrode array Cholinergic system Potassium channels
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S0969996126000252
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