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Ca2+-PP2B-PSD-95 axis: A novel regulatory mechanism of the phosphorylation state of Serine 295 of PSD-95.

The phosphorylation state of PSD-95 at Serine 295 (Ser295) is important for the regulation of synaptic plasticity. Although the activation of NMDA receptors (NMDARs), which initiates an intracellular calcium signaling cascade, decreases phosphorylated Ser295 (pS295) of PSD-95, the molecular mechanis...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Hauptverfasser: Takahiko Chimura, Toshiya Manabe
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science (PLoS) 2024-01-01
Schriftenreihe:PLoS ONE
Online-Zugang:https://doi.org/10.1371/journal.pone.0313441
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