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A DNA replication-independent function of pre-replication complex genes during cell invasion in C. elegans.

Cell invasion is an initiating event during tumor cell metastasis and an essential process during development. A screen of C. elegans orthologs of genes overexpressed in invasive human melanoma cells has identified several components of the conserved DNA pre-replication complex (pre-RC) as positive...

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主要な著者: Evelyn Lattmann, Ting Deng, Michael Walser, Patrizia Widmer, Charlotte Rexha-Lambert, Vibhu Prasad, Ossia Eichhoff, Michael Daube, Reinhard Dummer, Mitchell P Levesque, Alex Hajnal
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science (PLoS) 2022-02-01
シリーズ:PLoS Biology
オンライン・アクセス:https://doi.org/10.1371/journal.pbio.3001317
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