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Calcitriol Protects against Acetaminophen-Induced Hepatotoxicity in Mice

Acetaminophen (APAP) overdose is one of the major causes of acute liver failure. Severe liver inflammation and the production of oxidative stress occur due to toxic APAP metabolites and glutathione depletion. Growing evidence has proved that vitamin D (VD) exerts anti-inflammatory and antioxidative...

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Autors principals: Supachaya Sriphoosanaphan, Pakkapon Rattanachaisit, Kanjana Somanawat, Natcha Wanpiyarat, Piyawat Komolmit, Duangporn Werawatganon
Format: Artigo
Idioma:Inglês
Publicat: MDPI AG 2023-05-01
Col·lecció:Biomedicines
Matèries:
vitamin D
calcitriol
acetaminophen
APAP
hepatotoxicity
liver injury
Accés en línia:https://www.mdpi.com/2227-9059/11/6/1534
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