Early concentrate starter introduction induces rumen epithelial parakeratosis by blocking keratinocyte differentiation with excessive ruminal butyrate accumulation

Introduction: Rumen epithelial parakeratosis, a common disease in ruminants caused by abnormalities in the ruminal stratified squamous epithelial keratinization process, negatively impacts ruminant health and performance. However, we still lack a comprehensive perception of the underlying mechanisms...

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Principais autores:	Kai Zhang, Yali Zhang, Jing Qin, Haining Zhu, Ning Liu, Daming Sun, Yuyang Yin, Shengyong Mao, Weiyun Zhu, Zan Huang, Junhua Liu
Formato:	Artigo
Idioma:	Inglês
Publicado:	Elsevier 2024-12-01
Series:	Journal of Advanced Research
Assuntos:	Rumen epithelium Keratinization Parakeratosis Single-cell RNA-sequencing Rumen epithelial organoid
Acceso en liña:	http://www.sciencedirect.com/science/article/pii/S2090123223004010
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