Laser-activatable oxygen self-supplying nanoplatform for efficiently overcoming colorectal cancer resistance by enhanced ferroptosis and alleviated hypoxic microenvironment

Abstract Background Colorectal cancer (CRC) is the second most deadly cancer worldwide, with chemo-resistance remaining a major obstacle in CRC treatment. Notably, the imbalance of redox homeostasis-mediated ferroptosis and the modulation of hypoxic tumor microenvironment are regarded as new entry p...

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Hlavní autoři:	Hao Jiang, Hailong Tian, Zhihan Wang, Bowen Li, Rui Chen, Kangjia Luo, Shuaijun Lu, Edouard C. Nice, Wei Zhang, Canhua Huang, Yuping Zhou, Shaojiang Zheng, Feng Gao
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Association for the Advancement of Science (AAAS) 2023-09-01
Edice:	Biomaterials Research
Témata:	Colorectal cancer Chemo-resistance Ferroptosis Chemo-photothermal therapy Hypoxia
On-line přístup:	https://doi.org/10.1186/s40824-023-00427-1
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