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PIEZO1 expression at the glio-vascular unit adjusts to neuroinflammation in seizure conditions

Mechanosensors are emerging players responding to hemodynamic and physical inputs. Their significance in the central nervous system remains relatively uncharted. Using human-derived brain specimens or cells and a pre-clinical model of mesio-temporal lobe epilepsy (MTLE), we examined how the mRNA lev...

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Tallennettuna:
Päätekijät: Valentin Garcia, Marine Blaquiere, Alicia Janvier, Noemie Cresto, Carla Lana, Athenais Genin, Helene Hirbec, Etienne Audinat, Adele Faucherre, Emmanuel L. Barbier, Sophie Hamelin, Philippe Kahane, Chris Jopling, Nicola Marchi
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Elsevier 2023-10-01
Sarja:Neurobiology of Disease
Aiheet:
Piezo1
Neuro-inflammation
Neuro-mechanobiology
Focal seizures
Astrocytes
Microglia
Linkit:http://www.sciencedirect.com/science/article/pii/S0969996123003121
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