Apical Restriction of the Planar Cell Polarity Component VANGL in Pancreatic Ducts Is Required to Maintain Epithelial Integrity

Summary: Cell polarity is essential for the architecture and function of numerous epithelial tissues. Here, we show that apical restriction of planar cell polarity (PCP) components is necessary for the maintenance of epithelial integrity. Using the mammalian pancreas as a model, we find that compone...

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主要な著者:	Lydie Flasse, Siham Yennek, Cédric Cortijo, Irene Seijo Barandiaran, Marine R.-C. Kraus, Anne Grapin-Botton
フォーマット:	Artigo
言語:	Inglês
出版事項:	Elsevier 2020-05-01
シリーズ:	Cell Reports
主題:	planar polarity pancreas architecture development apical PCP VANGL
オンライン･アクセス:	http://www.sciencedirect.com/science/article/pii/S2211124720306306
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