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CCR2 macrophage response determines the functional outcome following cardiomyocyte transplantation

Abstract Background The immune response is a crucial factor for mediating the benefit of cardiac cell therapies. Our previous research showed that cardiomyocyte transplantation alters the cardiac immune response and, when combined with short-term pharmacological CCR2 inhibition, resulted in diminish...

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Tallennettuna:
Päätekijät: Praveen Vasudevan, Markus Wolfien, Heiko Lemcke, Cajetan Immanuel Lang, Anna Skorska, Ralf Gaebel, Anne-Marie Galow, Dirk Koczan, Tobias Lindner, Wendy Bergmann, Brigitte Mueller-Hilke, Brigitte Vollmar, Bernd Joachim Krause, Olaf Wolkenhauer, Gustav Steinhoff, Robert David
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: BMC 2023-08-01
Sarja:Genome Medicine
Aiheet:
Immunocompromised
Myocardial infarction
Machine learning
Macrophages
Single-cell
Cell therapy
Linkit:https://doi.org/10.1186/s13073-023-01213-3
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