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The doublecortin-family kinase ZYG-8DCLK1 regulates microtubule dynamics and motor-driven forces to promote the stability of C. elegans acentrosomal spindles.

Although centrosomes help organize spindles in most cell types, oocytes of most species lack these structures. During acentrosomal spindle assembly in C. elegans oocytes, microtubule minus ends are sorted outwards away from the chromosomes where they form poles, but then these outward forces must be...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Emily R Czajkowski, Yuntong Zou, Nikita S Divekar, Sarah M Wignall
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science (PLoS) 2024-09-01
Saila:PLoS Genetics
Sarrera elektronikoa:https://doi.org/10.1371/journal.pgen.1011373
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