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Reduced surface expression of epithelial E-cadherin evoked by interferon-gamma is Fyn kinase-dependent.

Interferon gamma (IFNγ) is an important regulatory cytokine that can exert a pro-inflammatory effect in the gut, where it has been shown to increase epithelial permeability via disruption of the tight junctions. Here we investigated the potential for IFNγ to regulate the adherens junction protein E-...

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Váldodahkkit: David Smyth, Gabriella Leung, Maria Fernando, Derek M McKay
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: Public Library of Science (PLoS) 2012-01-01
Ráidu:PLoS ONE
Liŋkkat:http://europepmc.org/articles/PMC3371038?pdf=render
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