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Protective effect of cafestol against doxorubicin-induced cardiotoxicity in rats by activating the Nrf2 pathway

Doxorubicin (DOX) is an efficient antineoplastic agent with a broad antitumor spectrum; however, doxorubicin-associated cardiotoxic adverse effect through oxidative damage and apoptosis limits its clinical application. Cafestol (Caf) is a naturally occurring diterpene in unfiltered coffee with uniqu...

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Principais autores: Sara A. Al-Kenany, Nada N. Al-Shawi
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2023-06-01
Serija:Frontiers in Pharmacology
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Online dostop:https://www.frontiersin.org/articles/10.3389/fphar.2023.1206782/full
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