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Glial A30P alpha-synuclein pathology segregates neurogenesis from anxiety-related behavior in conditional transgenic mice

In Parkinson's disease (PD) patients, alpha-synuclein (α-syn) pathology advances in form of Lewy bodies and Lewy neurites throughout the brain. Clinically, PD is defined by motor symptoms that are predominantly attributed to the dopaminergic cell loss in the substantia nigra. However, motor deficits...

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Autori principali: Franz Marxreiter, Benjamin Ettle, Verena E.L. May, Hakan Esmer, Christina Patrick, Christine Lund Kragh, Jochen Klucken, Beate Winner, Olaf Riess, Jürgen Winkler, Eliezer Masliah, Silke Nuber
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2013-11-01
Serie:Neurobiology of Disease
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Accesso online:http://www.sciencedirect.com/science/article/pii/S0969996113001988
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