Soluble CD127 potentiates IL‐7 activity in vivo in healthy mice

Abstract Introduction Soluble forms of cytokine receptors can be involved in the endogenous regulation of cytokine activity. Soluble interleukin 7 receptor α (sCD127) naturally binds IL‐7, therefore there is interest in its potential application as an immunotherapeutic agent to regulate IL‐7. With t...

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Principais autores:	Nawaf A. Aloufi, Alaa K. Ali, Stephanie C. Burke Schinkel, Bengisu Molyer, Priscila O. Barros, Joanne E. McBane, Seung‐Hwan Lee, Jonathan B. Angel
格式:	Artigo
語言:	Inglês
出版:	Wiley 2021-12-01
叢編:	Immunity, Inflammation and Disease
主題:	CD4+ T‐cell CD8+ T‐cell interleukin‐7 (IL‐7) soluble IL‐7Rα (sCD127) T‐cell proliferation
在線閱讀:	https://doi.org/10.1002/iid3.530
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