PPARγ is critical for Mycobacterium tuberculosis induction of Mcl-1 and limitation of human macrophage apoptosis.

Peroxisome proliferator-activated receptor (PPAR)γ is a global transcriptional regulator associated with anti-inflammatory actions. It is highly expressed in alveolar macrophages (AMs), which are unable to clear the intracellular pathogen Mycobacterium tuberculosis (M.tb). Although M.tb infection in...

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Hlavní autoři:	Eusondia Arnett, Ashlee M Weaver, Kiersten C Woodyard, Maria J Montoya, Michael Li, Ky V Hoang, Andrew Hayhurst, Abul K Azad, Larry S Schlesinger
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Public Library of Science (PLoS) 2018-06-01
Edice:	PLoS Pathogens
On-line přístup:	https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1007100&type=printable
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