Antisense Oligonucleotide Inhibition of MicroRNA-494 Halts Atherosclerotic Plaque Progression and Promotes Plaque Stabilization

We have previously shown that third-generation antisense (3GA) inhibition of 14q32 microRNA (miRNA)-494 reduced early development of atherosclerosis. However, patients at risk of atherosclerotic complications generally present with advanced and unstable lesions. Here, we administered 3GAs against 14...

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Autori principali:	Eva van Ingen, Amanda C. Foks, Mara J. Kröner, Johan Kuiper, Paul H.A. Quax, Ilze Bot, Anne Yaël Nossent
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Elsevier 2019-12-01
Serie:	Molecular Therapy: Nucleic Acids
Accesso online:	http://www.sciencedirect.com/science/article/pii/S2162253119302689
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