Sustainable production of multimeric and functional recombinant human adiponectin using genome-edited chickens

Abstract Background Adiponectin (ADPN) plays a critical role in endocrine and cardiovascular functions, but traditional production methods, such as Escherichia coli and mammalian systems, have faced challenges in generating sufficiently active middle molecular weight (MMW) and high molecular weight...

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主要な著者:	Eunhui Yoo, Hee Jung Choi, Jin-Kyoo Kim, Young Min Kim, Jin Se Park, Jae Yong Han
フォーマット:	Artigo
言語:	Inglês
出版事項:	BMC 2024-05-01
シリーズ:	Journal of Biological Engineering
主題:	Adiponectin Chicken bioreactor Chicken oviduct magnum Genome-edited chicken High molecular weight ADPN Multimeric ADPN
オンライン･アクセス:	https://doi.org/10.1186/s13036-024-00427-2
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