A Y-chromosome shredding gene drive for controlling pest vertebrate populations

Self-replicating gene drives that modify sex ratios or infer a fitness cost could be used to control populations of invasive alien species. The targeted deletion of Y sex chromosomes using CRISPR technology offers a new approach for sex bias that could be incorporated within gene-drive designs. We i...

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Detalles Bibliográficos

Autores principales:	Thomas AA Prowse, Fatwa Adikusuma, Phillip Cassey, Paul Thomas, Joshua V Ross
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	eLife Sciences Publications Ltd 2019-02-01
Colección:	eLife
Materias:	gene drive sex-ratio distortion pest control CRISPR resistance allele island conservation
Acceso en línea:	https://elifesciences.org/articles/41873
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