lncRNA IGFL2-AS1 mediates NSCLC chemoresistance via YBX1-induced HSPA1A/RAP1 activation

Abstract Background The development of drug resistance in cancer is associated with multiple malignant properties, including proliferative progression, metastasis, and stemness. Long noncoding RNAs (lncRNAs) reportedly contribute to multidrug resistance in lung cancer. However, functional and mechan...

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Autors principals:	Hongliang Dong, Yunxiu Xia, Jingjing Qi, Cuilan Liu, Fei Wang, Bingjie Cui, Weiwei Chen, Wenwen Lv, Nailiang Zhai, Jiong Deng, Yong Yu, Fangling Ning, Clemens A. Schmitt, Jing Du
Format:	Artigo
Idioma:	Inglês
Publicat:	BMC 2025-11-01
Col·lecció:	Cellular & Molecular Biology Letters
Matèries:	Lung cancer Drug resistance IGFL2-AS1 YBX1 HSPA1A
Accés en línia:	https://doi.org/10.1186/s11658-025-00808-5
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