Preventing surgery-induced natural killer cell suppression and metastases by inhibiting PI3K-gamma signaling in myeloid-derived suppressor cells

Background Myeloid-derived suppressor cells (MDSCs) have a dominating presence in the postoperative period, mediating the suppression of natural killer (NK) cells and promoting cancer metastases after surgery. However, their phenotype and effects on postoperative cellular immunity remain incompletel...

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Autori principali:	Rebecca C Auer, Michael A Kennedy, Natasha Kekre, Ismael Samudio, Michele Ardolino, David P Cook, Leonard Angka, Gayashan Tennakoon, Andre B Martel, Marisa Market, Christiano Tanese de Souza, Emma Cummins, Barbara C Vanderhyden
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	BMJ Publishing Group 2026-01-01
Serie:	Journal for ImmunoTherapy of Cancer
Accesso online:	https://jitc.bmj.com/content/14/1/e013304.full
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