Silent Propagation of Classical Scrapie Prions in Homozygous K222 Transgenic Mice

Classical scrapie affects sheep and goats. To control prevalence in sheep, the European Union initiated breeding programs targeting resilient genotypes. Although certain goat polymorphisms, such as Q222K, are linked to resistance, specific breeding programs have not been implemented. Hemizygous tra...

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Autores principales:	Natalia Fernández-Borges, Alba Marín-Moreno, Juan Carlos Espinosa, Sara Canoyra, Olivier Andréoletti, Juan María Torres
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Centers for Disease Control and Prevention 2025-12-01
Colección:	Emerging Infectious Diseases
Materias:	classical scrapie prions and related diseases goat mouse resistant genotype silent prion carrier
Acceso en línea:	https://wwwnc.cdc.gov/eid/article/31/12/25-0302_article
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