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Synergistic antiproliferative effects of the cisplatin and nimotuzumab combination through modulation of EGFR/MEK/ERK signaling in neuroblastoma

This study investigated the synergistic cytotoxic effect of cisplatin and nimotuzumab combination in neuroblastoma cells and their impact on EGFR/MEK/ERK signaling. Human neuroblastoma cells (SH-SY5Y) were treated with cisplatin (1, 3, and 10 µM), nimotuzumab (10 µM), and their combinations (1 µM Ci...

Celý popis

Uloženo v:
Hlavní autoři: Serhat Korkmaz, Elif Kaga, Sadik Kaga, Zafer Soylemez, Gizem Fatma Erguner, Evrim Suna Arikan Soylemez
Médium: Artigo
Jazyk:Inglês
Vydáno: Society of Turaz Bilim 2025-04-01
Edice:Medicine Science
Témata:
neuroblastoma
cisplatin
nimotuzumab
combination therapy
On-line přístup:https://www.medicinescience.org/?mno=240854
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