TrieDedup: a fast trie-based deduplication algorithm to handle ambiguous bases in high-throughput sequencing
Abstract Background High-throughput sequencing is a powerful tool that is extensively applied in biological studies. However, sequencers may produce low-quality bases, leading to ambiguous bases, ‘N’s. PCR duplicates introduced in library preparation are conventionally removed in genomics studies, a...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BMC
2024-04-01
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| Schriftenreihe: | BMC Bioinformatics |
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| Online-Zugang: | https://doi.org/10.1186/s12859-024-05775-w |
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