Enhanced measures of neoantigenicity capture unique tumor-immune interactions across primary melanoma subtypes

Abstract Background As immune checkpoint inhibitor therapies move toward treatment of clinically high-risk localized primary melanoma, there is an increasing need for clear understanding of the tumor-immune interaction across primary melanoma subtypes. Tumor genomic properties play a crucial role in...

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Detalhes bibliográficos

Principais autores:	Eva R. Shteinman, Grace H. Attrill, Nigel G. Maher, Kiran Gnana, Venkateswar Addala, Yizhe Mao, Umaimainthan Palendira, Jordan W. Conway, Andrew J. Colebatch, Nicola Waddell, Nicholas K. Hayward, John V. Pearson, Georgina V. Long, Richard A. Scolyer, James S. Wilmott, Ismael A. Vergara
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2026-05-01
coleção:	Genome Medicine
Assuntos:	Primary melanoma Cancer genomics Cancer immunology Whole-genome sequencing Neoantigens Tumor mutational burden
Acesso em linha:	https://doi.org/10.1186/s13073-026-01673-3
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