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Glutathione overproduction mediates lymphoma initiating cells survival and has a sex-dependent effect on lymphomagenesis

Abstract Lymphoid tumor patients often exhibit resistance to standard therapies or experience relapse post-remission. Relapse is driven by Tumor Initiating Cells (TICs), a subset of tumor cells capable of regrowing the tumor and highly resistant to therapy. Growing cells in 3D gels is a method to di...

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Principais autores: Alberto H.-Alcántara, Omar Kourani, Ana Marcos-Jiménez, Patricia Martínez-Núñez, Estela Herranz-Martín, Patricia Fuentes, María L. Toribio, Cecilia Muñoz-Calleja, Teresa Iglesias, Miguel R. Campanero
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2024-07-01
coleção:Cell Death and Disease
Acesso em linha:https://doi.org/10.1038/s41419-024-06923-z
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